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The researchers found that the mechanism by which metformin stimulates GLP-1 release involves two G-protein-coupled receptors, the M3 cholinergic receptor and the GRP receptor ( In summary, metformin can promote GLP-1 secretion in the gastrointestinal tract through several mechanisms
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doi: 10.2105/AJPH.2013.301597, [DOI] [PMC free article] [PubMed] [Google Scholar] Boye K., Ross M., Mody R., Konig M., Gelhorn H
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